Advancements in Nanozyme-Based Drug Delivery for Targeted Cancer Therapy

DOI: https://doi.org/10.63345/ijrmp.org.v10.i3.3

Shweta Chouhan

Independent Researcher

Indore, Madhya Pradesh, India

Abstract

Nanozymes, nanomaterials endowed with enzyme-mimicking catalytic activities, have emerged as a transformative platform in biomedical applications. Their integration into drug delivery systems for targeted cancer therapy has opened new avenues for precision medicine by combining therapeutic efficiency with diagnostic capability. This manuscript reviews the evolution and application of nanozyme-based drug delivery vehicles, emphasizing their catalytic performance, biocompatibility, and potential for overcoming conventional drug resistance. We discuss recent advancements in nanozyme synthesis, surface modification techniques, and drug encapsulation strategies that enhance tumor-targeting specificity. Furthermore, we explore in vitro and in vivo results that highlight the promise of these systems in reducing systemic toxicity while increasing therapeutic efficacy. The manuscript concludes with an analysis of current challenges, including issues related to stability, potential immunogenicity, and scalability for clinical translation, and provides perspectives on future research directions in nanozyme-based targeted cancer therapy.

Keywords

Nanozymes; targeted drug delivery; cancer therapy; enzyme mimics; nanomedicine.

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