DOI: https://doi.org/10.63345/ijrmp.v12.i11.4
Soham Deshmukh
Independent Researcher
Maharashtra, India
Abstract
Cancer remains one of the leading causes of mortality worldwide, demanding innovative therapeutic strategies that overcome the limitations of conventional treatments. In recent years, gold nanoparticles (AuNPs) have emerged as promising vehicles for targeted drug delivery due to their unique physicochemical properties, biocompatibility, and ease of surface modification. This manuscript provides an in-depth exploration of the application of AuNPs in targeted cancer therapy. The discussion spans the synthesis and functionalization of AuNPs, their mechanism in delivering therapeutic agents directly to tumor sites, and the advantages and challenges associated with their use. A detailed literature review up to 2022 is presented to contextualize the recent advancements in the field. Furthermore, the manuscript outlines a methodology for evaluating the efficacy of AuNP-based drug delivery systems, reports experimental results from recent studies, and discusses the potential of AuNPs to enhance drug bioavailability while minimizing side effects. The findings indicate that while gold nanoparticle platforms offer significant promise for precision oncology, further research is essential to address current limitations and optimize clinical applications.
Keywords
Gold Nanoparticles; Targeted Drug Delivery; Cancer Treatment; Nanomedicine; Oncology; Chemotherapy; Biosafety; Functionalization; Precision Medicine
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