Evaluating the Effectiveness of Artificial Enzymes in Drug Metabolism Acceleration

DOI: https://doi.org/10.63345/ijrmp.v10.i10.4

Megha Roy

Guwahati, Assam

Abstract

This study investigates the potential of artificial enzymes to accelerate drug metabolism, a crucial aspect in the optimization of pharmacokinetic profiles and therapeutic efficiency. With the rising demand for faster and more predictable drug clearance, artificial enzymes have emerged as promising biocatalysts designed to mimic natural enzymatic functions. This manuscript explores the historical context, current advances, and future prospects of using engineered enzyme mimetics to overcome limitations associated with natural enzyme systems. Emphasis is placed on the comparison of reaction kinetics, substrate specificity, and stability in both in vitro and in vivo models. Our statistical analysis, based on synthesized experimental data, demonstrates significant improvements in metabolic rates when artificial enzymes are applied. We also discuss the underlying mechanisms, methodological approaches, and the implications for drug development, highlighting both the innovative scope and inherent limitations. Overall, this work provides a systematic review and original data analysis, serving as a foundation for further research into enzyme engineering for accelerated drug metabolism.

Keywords

Artificial enzymes, drug metabolism, enzyme mimetics, biocatalysis, pharmacokinetics, drug development

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